第314回化学システム工学専攻公開セミナー Progress in Continuous Pharmaceutical Manufacturing and Technoeconomic Optimization
- 日時
- 2018年2月19日（月） 10:30～12:00
- 場所
- 東京大学工学部3号館大会議室1（6C07号室）
| 講演題目 | Progress in Continuous Pharmaceutical Manufacturing and Technoeconomic Optimization |
|---|---|
| 講演者 | Dr Dimitrios I. Gerogiorgis Lecturer, Institute for Materials & Processes (IMP), School of Engineering, University of Edinburgh, UK |
| 概要 | Continuous Pharmaceutical Manufacturing (CPM) emerges as a ground-breaking technology which can invigorate the global pharmaceutical industry by sustainably fostering its agility and the affordability of healthcare for large populations: advances in continuous organic synthesis routes which induce demonstrations of full (end-to-end) continuous pharmaceutical production and comparative economic analyses explicitly illustrate CPM advantages, thus attracting the strong interest of global pharmaceutical corporations and authoritative regulatory bodies. Remarkable corporate investments in production-scale CPM facilities illustrate the value of this novel paradigm. This lecture will focus on our successful applications of process systems engineering methodologies (process synthesis, modelling, simulation and optimisation) towards evaluating technical efficiency, environmental impact and economic viability of several new continuous processes for manufacturing Active Pharmaceutical Ingredients (APIs) of high importance (ibuprofen, artemisinin, diphenhydramine, cyclosporine), based on relevant continuous flow synthesis precedents. Original process design, economic and environmental impact results will be presented. |
| 世話人 | 杉山 弘和（内線27227） |